Infant botulism.
نویسندگان
چکیده
Infant botulism is a rare disease that affects infant less than 12 months of age. The illness results from absorption of botulinum toxin produced in situ by neurotoxigenic clostridia that can temporarily colonize the intestinal tract of infants. To date, all inhabited continents except Africa have reported cases of infant botulism. Recognition of cases seem directly related to physician awareness and clinical suspicion. This review summarizes microbiological, clinical and epidemiological features of infant botulism.
منابع مشابه
Infant Botulism: a Summary
Infant botulism is a rare paralytic disease caused by the microorganism Clostridium botulinum. If an infant swallows enough spores, the spores can colonize the large intestine, multiply and produce toxin. The toxin is absorbed into the body and carried to the nerve endings, which results in muscular impairment. Infant botulism differs from foodborne botulism in where and when the toxin is produ...
متن کاملFirst case of infant botulism caused by Clostridium baratii type F in California.
In late 2003 a severely hypotonic neonate, just 38 h old at onset of illness, was found to have infant botulism caused by neurotoxigenic Clostridium baratii type F. Environmental investigations failed to identify a source of this strain. This is the youngest patient reported to have infant botulism and the fifth instance of infant botulism caused by C. baratii type F.
متن کاملFirst report of an infant botulism case due to Clostridium botulinum type Af.
Most infant botulism cases worldwide are due to botulinum toxin types A and B. Rarely, Clostridium botulinum strains that produce two serotypes (Ab, Ba, and Bf) have also been isolated from infant botulism cases. This is the first reported case of infant botulism due to C. botulinum type Af worldwide.
متن کاملClinical mimics of infant botulism.
Since 1992, Human Botulism Immune Globulin has been provided by the California Department of Health Services to infants with probable infant botulism, the intestinal toxemia form of human botulism. Human Botulism Immune Globulin became available in California in 1992-1997 within a randomized, controlled, double-blinded, pivotal clinical trial and subsequently became available nationwide in 1998...
متن کاملRuth Koepke , Jeremy Sobel and Stephen S . Arnon Global Occurrence of Infant Botulism
OBJECTIVE. To summarize the worldwide occurrence of reported infant (intestinal toxemia) botulism cases since first recognition of the disease in 1976. PATIENTS AND METHODS.We collected information on infant botulism cases by active and passive surveillance, by provision of therapeutic Human Botulism Immune Globulin to suspected cases, and by searching the medical literature. We defined a case ...
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عنوان ژورنال:
- Annali dell'Istituto superiore di sanita
دوره 45 2 شماره
صفحات -
تاریخ انتشار 2009